Global trends of antibiotic-resistant genes

Antibiotic resistance is threatening a public health crisis, but genes that resist antibiotics lurk in the human microbiome. In order to understand the spread of antibiotic resistance worldwide, researchers in the Brito lab investigated these genes in microbiomes throughout the world. They found some pervasive genes and others that have serendipitously remained less widespread. They are investigating these underlying trends. Lead author on the paper is Brito lab Ph.D. student Peter Diebold.

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Clinically relevant antibiotic resistance genes are linked to a limited set of taxa within gut microbiome worldwide.” Diebold PJ, Rhee MW, Shi Q, Trung NV, Umrani F, Ahmed S, Kulkarni V, Deshpande P, Alexander M, Hoa NT, Christakis NA, Iqbal NT, Ali SA, Mathad JS, and Brito IL. Nature Communications. 14:7366. (2023)

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